5 Panel Drug Test and 5 Panel Rapid Test

The 5 panel drug test is the most common type of drug test available for individuals and employers. In particular, employers looking to institute a reliable drug testing program, a 5 panel drug test is an excellent option, as they are commonly used by the Department of Transportation (DOT) and other Federal testing.  For random drug testing, the 5 panel drug test is often utilized. 

Five panel drug screens check for the following substances:

Woman signing a paper

The 5 panel drug test is available as a Lab based test or as an instant rapid drug test.

The most popular instant test is the 5-panel often also called 5 panel rapid drug test.

The lab testing might be classified as a DOT LIKE or Expanded Opiate 5 Panel drug test and this is highly recommended.  With this version the 5-Panel DOT like includes: Marijuana, Cocaine, Phencyclidine (PCP), Amphetamines (+Methamphetamines, MDMA & MDA) & Opioids (including 6AM or Heroin, Codeine, Morphine, oxycodone, oxymorphone, hydrocodone & hydromorphone).  

The 5 panel drug test is also used for most non-regulated companies. It is available for rapid testing with same day results at our locations throughout the United States including all LabCorp and all Quest Diagnostics locations.

For probation testing often the 5 panel test is ordered as a 5 panel drug screen plus alcohol.  You can order here the 5 Panel + Alcohol Urine Drug Test.

5 Panel Test With Expanded Opiates


Our 5 panel drug screening tests can also include additional specimen validity testing and expanded testing for MDMA and Ecstasy, Methamphetamines, 6-Acetylmorphine (6-AM, a Metabolite of Heroin), Morphine, Codeine, Hydrocodone, Oxycodone, Hydromorphone, and Oxymorphone. This is referred to as expanded opiate testing or 5 Panel DOT Like drug test; sometimes referred to as opioids. A DOT requirement for DOT drug testing is the inclusion of the expanded opiates – Hydrocodone, Oxycodone, Hydromorphone, and Oxymorphone. This DOT requirement became effective October 1, 2017. Many non-regulated employer have followed along and now included these semi-synthetic opioids in their workplace drug testing programs.   

The opioid crisis in the United States has been a major issue in recent years, with millions of people becoming addicted to prescription painkillers and heroin. Pill mills, which are clinics or doctors’ offices that prescribe large quantities of opioids without proper medical justification, have played a significant role in fueling the crisis. These pill mills often operate as cash-only businesses and provide prescriptions to patients without conducting thorough medical evaluations. This has led to widespread abuse and addiction, as well as an increase in overdose deaths across the country. The government has been cracking down on pill mills in an effort to combat the crisis, but the problem persists in many areas. It is critical to include the expanded opiates or opioids in a workplace drug testing program.

At National Drug Screening we believe the 5 panel drug test with expanded opiates has become the standard drug test panel used for employee drug testing. US Companies not regulated by DOT should check with their drug testing venders to make sure they are getting the correct 5 panel drug test. Many times we see the older panel being used and the expanded opiates not included. Look for an experienced and accredited drug testing provider.  

National Drug Screening will work prudently with you in order to provide you with exactly what you need individually, or for your business. We offer drug testing solutions for individuals and employers in every city in the United States.

– METYesYes
– MDMAYesYes
– CODYesYes
– MORYesYes
– HEROYesYes
– HYDNoYes
– OXYNoYes

Multi-Panel Drug Tests

All drug tests generally follow the same procedure where each panel is a specific drug being tested. For instance, a 5-panel drug screening tests for 5 drugs, whereas a 10 panel drug screening tests for 10 drugs.

The standard 5-panel drug screening urine test is the most common and is routinely utilized by private employers, as well as government agencies, since it tests for the 5 most habitually abused substances: Marijuana, Cocaine, Opiates, PCP and Amphetamines/Methamphetamines.

The 5-panel drug test is the nationwide standard for the Federal government’s Mandatory Guidelines for Workplace Drug Testing, which is why it is used for the majority of workplace drug screenings. For instance, the DOT (Department of Transportation) requires their truck drivers to undergo a five panel urine drug test prior to employment and randomly throughout the year during their term of employment. DOT truck drivers are also required to submit to a 5-panel drug test after an accident, or if reasonable suspicion exists that a driver may be using illegal drugs.


For non-regulated employers, individuals and probation:

 Instant Rapid Urine Test – 5 Panel Test 

Instant Rapid Urine Test – 10 Panel Test 

These are available from our partner laboratories Quest Diagnostics and LabCorp. Call 866-843-4545 or click above to order.

one step multi panel drug test

More About 5 Panel Drug Tests

The drugs below are the most commonly abused substances that National Drug Screening will screen for during a 5 panel drug screen test. Both urine and hair tests are available nationwide for employers and individuals. Urine testing is able to detect the following drugs between 4-7 days after use, while a 5 panel hair test can detect these drugs up to 90 days after use.


Marijuana, also known as tetrahydrocannabinol, or THC, is probably the most common substance that individuals are found positive for on drug screening tests. It is found naturally, and exclusively, in the marijuana, or cannabis plant. A pharmaceutical formulation, which is basically synthetic THC, is available by prescription and is known by the brand name Marinol. Marijuana can be found in various forms, including the dried flower buds, processed into hash or oil, or baked into foods such as cookies or brownies.

Users can either smoke the hash, oil or dried buds, or eat the baked goods. Inhalation or consumption of cannabis produces mild to moderate analgesic effects. This includes feelings of relaxation and euphoria, but can also lead to feeling anxious or paranoid. Marijuana is also used to relieve pain since it alters transmitter release in the periaqueductal gray (PAG) and the dorsal root ganglion in the spinal cord.

THC has also been known to stimulate the appetite and is prescribed for such purposes when a suppressed appetite is the effect of a disease or cancer treatment such as radiation therapy. Although many states recognize the medicinal uses of marijuana and allow its legal prescription, the Federal government classifies it as a schedule 1 drug with no medicinal value. Therefore, THC is still tested for in all standard 5 panel drug tests, regardless if it is legalized in a particular state.

The DOT strictly prohibits the use of marijuana for safety sensitive employees including truck drivers. Employers in all States have a right to implement a drug-free workplace program which can include a policy which prohibits marijuana use and allows the employer to have disciplinary consequences for a positive marijuana drug test.

If you need a drug test for marijuana or THC, order the 5 panel drug test.


Cocaine, or coke, is a strong stimulant generally used as a recreational drug. It is processed from the leaves of the cocoa plant that is native to South America. Cocaine is usually in the form of a white powder and is often mixed with similar looking powders, such as baking soda, as fillers. It is usually inhaled or snorted, or injected in order to produce its effects of wakefulness and/or numbing. It is also used as an appetite suppressant.

The Federal government recognizes cocaine as a Schedule 2 drug with a much higher potential for addiction and abuse than Schedule 1 drugs. Habitual use of cocaine is likely to result in physical or psychological dependence so it is considered very dangerous and is tested for in all 5-panel drug tests.

If you need a drug test for Cocaine, order the 5 panel drug test.


Amphetamines are usually found in pill form and are susceptible to artificial fillers much like cocaine, since it is often crushed by the user for snorting. Some common forms include Adderall and Ritalin, which are used to treat ADD and ADHD. Amphetamines are also stimulants and appetite suppressants, much like cocaine but to a lesser extent. They are well known to be used among college and high school students as a “study drug” since they allow the user to stay alert and awake longer, and be much more focused.

Methamphetamine, or “meth”, is a form of amphetamine that is found as a powder or in crystallized form and is highly dangerous and addictive. Meth creates a strong and violent addiction, and requires a larger amount with each use to experience the same high. Prolonged use destroys dopamine receptors and will make it impossible to feel pleasure. Amphetamine, and Methamphetamine, is considered a schedule 2 drug with high potential for abuse resulting in dangerous physical dependence or psychological addiction. Although it is available by prescription, it is illegal to use amphetamines recreationally.

The five panel drug test when detecting Amphetamine, and Methamphetamine will also identify 3, 4-methylenedioxy-methamphetamine (MDMA) a synthetic drug known as Ecstasy or Molly.

If you need a drug test for Amphetamine or Methamphetamine, order the 5 panel drug test.


Opiates are used to create drugs such as heroin, and other medicinal painkillers like morphine. It is derived from the opium poppy plant originating in South-East Asia. Opiates increase euphoria and reduce pain in the user. They can be snorted, smoked or injected. Both physical dependence and psychological addiction is very strong. There are many variations, some legitimately used in the medical field, so the DEA schedules them differently. For example, heroin is a schedule 1 while Vicodin is a schedule 3 drug.

If you need a test for heroin or other opiates, order the 5 panel drug test with expanded opiates.


Phencyclidine, also known as PCP or angel dust, is legitimately made as an animal tranquilizer, which is often stolen or made in laboratories illegally. It is either in the form of a clear, yellowish liquid or in a powder. PCP is taken in a variety of different ways, including snorting, smoking, and injecting. The effects are dangerous hallucinations, and prolonged use can result in states similar to schizophrenia. PCP is considered by the Federal government to be a schedule 2 substance.

If you need a test for Phencyclidine, also known as PCP, order the 5 panel drug test with expanded opiates.

Purchase Your 5 Panel Drug Test

Although most private employers in the United States have a variety of options when it comes to the type of drug test (4 panel drug test, 5 panel drug test, 7 panel drug test, 10 panel drug test, etc.), as well as the testing specimen (blood, urine, hair, or saliva), most stick with the industry standard 5 panel drug screening test. For that reason, unless you have the need to test for a specific substance that is not included in the five panel drug test, National Drug Screening recommends sticking with the: 5 Panel Drug Test or 5 Panel Drug Test with Expanded Opiates (DOT Like).

For the fastest service possible and immediate testing, please go to