10 Panel Drug Test

The  10-panel urine drug  test is very popular for employers, individuals and probation drug testing.  This ten-panel drug test is screening and confirming for both illicit drugs and illicit use of prescription drugs.  There is a standard 10-panel drug test along with the 10—panel drug test with expanded opiates.   The 10—panel drug test with expanded opiates is often called a 10 panel DOT Like.

Standard 10 Panel Drug Test

10 Panel with Expanded Opiates (DOT Like)

The term DOT Like is referring to the first five drugs and having them test exactly like what is required by the United Stated Department of Transportation  (DOT). If you note above the 10 Panel with Expanded Opiates (DOT Like) has added metabolites being test for on the Amphetamines panel and the Opiates panel. The 10 Panel with Expanded Opiates (DOT Like) is highly recommended for a more inclusive testing panel recognizing drug abuse we are currently seeing in the United States.

Instant testing or Point of Collection Testing (POCT) is also available at our Quest Diagnostics or LabCorp testing facilities.  This ten-panel instant test includes marijuana, PCP, amphetamines, methamphetamines, opiates, cocaine, benzodiazepines, barbiturates, methadone, propoxyphene & oxycodone. With the oxycodone added it has 11 metabolites, but we call it a 10-panel instant drug screen. When instant testing screens for a metabolite as positive, the specimen must go to the lab for confirmation testing. Order Now Your 10-Panel Instant Drug Test.      

Drug usage amongst employees in a workplace or, worse yet, while operating heavy machinery for transportation needs, is not just unsafe, it is unethical and illegal.

People that use drugs while working are putting themselves and others at risk through a much higher chance of error thanks to the altered state of consciousness, drugs at work can cause, or the residual effects that still linger when a person tries to work after the immediate effects have worn off.

Drugs can have a variety of different effects, from the outright hallucinations of psychedelic substances to the manic behavior of cocaine that can severely impact both decision making and professional relationships in the workplace.

Lets learn about the 10-Panel Drug Test which can be a lab test or an instant (rapid) test.  With the instant test if positive a confirmation test is needed at the lab with gas chromatography, mass spectrometry (GC/MS).  The ten panel drug test is a combination of street drugs or illicit drugs and prescribed drugs. An outcome of a negative result is always preferred.

10 panel drug testing vials

When ordering a 10 panel drug test, be sure you are getting what you are asking for. The 10 panel drug test includes marijuana, PCP, amphetamines, opiates (codeine, morphine & heroin), cocaine, benzodiazepines, barbiturates, methadone, propoxyphene, & methaqualone (Quaaludes). This 10 panel does not include Opioids or synthetic opiates such as Hydrocodone, Hydromorphone, Oxycodone and Oxymorphone. These are included in what is called the expanded opiate testing or DOT Like testing in this case also referred to as a 10 pane DOT Like drug test.

DOT Like indicates that the first 5 drugs on the panel are exactly the same as the required testing for employers regulated by the Department of Transportation (DOT).

Casting A Wide Net

A 10 panel drug test is merely one configuration of a general type of drug testing known as panel drug testing. Panel drug tests are designed to screen for numerous types of drugs from only one sample, which makes them very efficient, since it means that employers don’t have to lose too much time from workers repeatedly giving multiple samples, and the employees themselves don’t experience as much of an imposition on their time or their biology with too many tests.

The industry has a standard panel of drugs typically in the 10 panel drug test. This panel includes: AMP-Amphetamines (including MAMP-Methamphetamine, MDMA-Ecstasy); COC-Cocaine: OPI-Opiates (including codeine, morphine and heroin); PCP-Phencyclidine; THC-Marijuana; BZO-Benzodiazepines BAR-Barbiturates; MTD-Methadone; PPX-Propoxyphene; and Meth – Methaqualone. National Drug Screening always recommends ordering the 10 panel drug test with expanded opiates. 

While we offer the 10 panel drug test, this type of testing is available for different numbers of drugs depending on the professional requirements a company may have. There are 5, 7, 10, and 12 panel drug tests available on the general market, but all of them fulfill the same function; with just one sample, they can screen for a select number of drugs. All of our drug test options with urine or hair can be ordered online – Order Now.

What Drugs Are In The 10 Panel Drug Test

Amphetamines & Methamphetamine

These are addictive stimulant drugs that strongly activate certain systems in the brain. Both pharmaceutical and street forms of amphetamine have a very high potential for abuse and carry significant risk of addiction. Methamphetamine or Meth is closely related chemically to amphetamine, but the central nervous system effects of methamphetamine are greater. Also included is MDMA, often called ECSTASY and is a synthetically produced drug.


Cocaine or coke is a powerfully addictive drug of abuse. Individuals who have tried cocaine have described the experience as a powerful high that gave them a feeling of supremacy. However, once someone starts taking cocaine, one cannot predict or control the extent to which he or she will continue to use the drug. Common street names include Blow, Coca, Coke, Crack, Flake, Snow, and Soda Cot.


Referring to including codeine, morphine, and heroin; opiates, sometimes referred to as narcotics, are a group of drugs which are used medically to relieve pain, but also have a high potential for abuse. Some opiates come from a resin taken from the seed pod of the Asian poppy. Heroin (“junk,” “smack”) accounts for 90 percent of the opiate abuse in the United States. Sometimes opiates with legal medicinal uses also are abused.

Expanded Opiates

These are the pain relief medications that sometimes get abused. These drugs include hydrocodone, oxycodone, hydromorphone, and oxymorphone and can be very addictive. A drug test must be ordered with expanded opiates in order for these drugs to be detected. Often folks become addicted to these drugs and when the prescriptions run out this can lead to heroin use.

PCP or Phencyclidine

PCP is a synthetic drug sold as tablets, capsules, or white or colored powder. It can be snorted, smoked, or eaten. Developed in the 1950s as an IV anesthetic, PCP was never approved for human use because of problems during clinical studies, including intensely negative psychological effects. PCP is predominantly abused by young adults and high school students. PCP’s effects include sedation, immobility, amnesia, and marked analgesia.

Marijuana or THC

The main active chemical in marijuana is THC (delta-9-tetrahydrocannabinol). Short-term effects of marijuana use include problems with memory and learning; distorted perception; difficulty in thinking and problem-solving; loss of coordination; and increased heart rate, anxiety, and panic attacks. Marijuana used can lead to many negative consequences, including bad grades, broken friendships, family problems and trouble with the law.


These are depressants that produce sedation and hypnosis, relieve anxiety, and muscle spasms, and reduce seizures. Benzodiazepines slow down the central nervous system and may cause sleepiness and relaxed mood. The most common benzodiazepines are the prescription drugs Valium®, Xanax®, Halcion®, Ativan®, and Klonopin®. Tolerance can develop, and this can often lead to abuse. Benzodiazepines are associated with amnesia, hostility, irritability, and vivid or disturbing dreams.


These are depressants that produce a wide spectrum of central nervous system depression from mild sedation to coma. They also have been used as sedatives, hypnotics, anesthetics, and anticonvulsants. Barbiturates are abused by swallowing a pill or injecting a liquid form. Barbiturates are generally abused to reduce anxiety, decrease inhibitions, and treat unwanted effects of illicit drugs. Barbiturates can be extremely dangerous because overdoses can occur easily and lead to death.


This is a synthetic (man-made) narcotic. Methadone is a Schedule II narcotic under the Controlled Substances Act. While it may legally be used under a doctor’s supervision, its non-medical use is illegal. It is often taken to help heroin addiction. Methadone is often abused, and this can lead to can lead to psychological dependence. Many communities have methadone clinics that provide medication-assisted treatment using methadone as an opioid agonist medication that reduces cravings and blocks euphoric effects of other opioids.


Similar to methadone, this is a is a narcotic analgesic compound. It is also referred to an opioid pain reliever used to treat mild to moderate pain. In 2010 the U.S. Food and Drug Administration (FDA) is recommended against continued prescribing and use of the pain reliever propoxyphene because new data show that the drug can cause serious toxicity to the heart, even when used at therapeutic doses. Although this drug is no longer on the market it still has a presence on the streets.


This drug is often called quaaludes and difficult to find in the United States. Laboratories are still seeing some quaalude positives on drug test. During the 70s and 80s, quaaludes gained significant popularity as a favored party drug among America’s affluent class, as depicted in the renowned scenes from The Wolf of Wall Street. These sedatives were known for their potent sedative effects.

Screening Your Preferences

The 10 panel drug test, like all panel drug tests, can be configurable. The specific drugs that you would like to have screened can be included in the panel, while the drugs that aren’t relevant or common to your industry can be left out. So, for example, if you are more concerned with detecting the presence of prescription drugs rather than proscribed substances such as cocaine, the selected substances can be included in your test. If your focus is more specifically on opiates and opioids than anything else, it’s possible for those particular drugs to be configured into your test requirements. Note that custom panels might be more expensive than the standard panels.

Ultimately, the major advantage of a 10 panel drug test is that the choice is yours. Different companies will have different interests in terms of what they would like to screen for. A company with an extensive trucking fleet is going to focus on a different range of drug tests from a company that is largely confined to traditional office activities. A 10 panel drug test can cater to both. Note that DOT regulated trucking companies are currently required to use the DOT 5 panel drug test.


How It Works

The 10 panel drug test, as with the other panel tests, is very simple to administer because it relies on a urine sample. Urine testing works in a simple fashion; many drugs used will linger in the body even days after usage. Alcohol is not one of these substances, as a single ounce can pass through the system and evade drug panel detection within 90 minutes of consumption. But for other drugs such as marijuana or methadone, there are certain metabolites that will remain in the system for 48 hours or more. Once the urine sample has been donated, the sample is then sent to a SAMHSA certified laboratory for testing and finally laboratory the data send to licensed medical review officer (MRO) to interpret the results. If the results are negative, the subject is clean, but if any of the substances included as part of your selected test comes out positive, further testing for more specific confirmation and MRO review will occur before you are notified.

Doctor holding a urine sample
It’s important to note that this testing merely confirmed the presence of drugs in the system for recent usage. This is not a sobriety test to indicate levels of impairment or performance. Once the information has been assessed and confirmed, it is up to you to decide what you would like to do with the results, but it is not a medical diagnosis of a subject’s fitness or condition at the time of testing, merely an acknowledgement of the recent use and presence of drugs in the system.

If you’d like to know more about workplace drug screening and how it can help your pre-employment or regular business activities, contact us for more information. We have a full staff on standby to professionally review your drug testing program and inform you of the results and we are fully compliant with State and Federal regulations.