Specimen validity testing (SVT) often called testing for nitrates or Test Sure (TS) is is performed on a drug screen specimen to detect substitution, adulteration, or dilution.
Specimen validity testing is performed simultaneously with the initial drug screens. Depending upon the drug screen and the specimen validity results, the laboratory will release (1) both the drug screen and the specimen validity test results, (2) the specimen validity test results only, or (3) the drug screen results only.
The nitrite threshold level established by the Federal Government is 500ug/mL. This is based on the level at which a drug screen may be impacted by this adulterant and by which no normal physiological level has been detected.
How would a drug test be evaluated when nitrates are 490 ng/mL?
A: The nitrite result would be negative, as this level would not interfere with our testing process. The drug test(s) ordered would be conducted and reported following standard operating procedures.
At Quest Diagnostics, TestSure adulterant testing helps to ensure that your donor's urine sample has not been adulterated. When you request TestSure, Quest will screen the specimen for a variety of compounds by using state-of-the-art secondary testing methods. The results are then provided to the medical review officer (MRO) for interpretation.